BarDurham, NC

106 Main

Closed · opens tomorrow 12:00 PM

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Opening hours

Closed · opens tomorrow 12:00 PM

Weekly opening hours of 106 Main
Monday	Closed
Tuesday	12:00 PM – 10:00 PM
Wednesday	12:00 PM – 10:00 PM
Thursday	12:00 PM – 10:00 PM
Friday	12:00 PM – 12:00 AM
Saturday	12:00 PM – 12:00 AM
Sunday	Closed

Local time in Durham: 11:10 PM (EDT). Holiday hours may differ – call (919) 593-0560 to confirm.

Location & directions

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106 East Main Street
Durham, NC

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About 106 Main

Located at 106 East Main Street in Durham, North Carolina, 106 Main is a bar. It is one of 430 places to eat and drink we list in Durham.

106 Main is open 5 days a week, usually 12:00 PM – 10:00 PM (closed Monday and Sunday). Night owls can stop by until 12:00 AM on Friday and Saturday.

For questions or orders, call (919) 593-0560.

Quick facts

Category: Bar
Address: 106 East Main Street, Durham, NC
Phone: (919) 593-0560
Hours: Open 5 days a week, usually 12:00 PM – 10:00 PM (closed Monday and Sunday)
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for bars and this venue’s opening hours – not live data.

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Frequently asked questions

What are 106 Main's opening hours?

Open 5 days a week, usually 12:00 PM – 10:00 PM (closed Monday and Sunday). Monday: Closed; Tuesday: 12:00 PM – 10:00 PM; Wednesday: 12:00 PM – 10:00 PM; Thursday: 12:00 PM – 10:00 PM; Friday: 12:00 PM – 12:00 AM; Saturday: 12:00 PM – 12:00 AM; Sunday: Closed.

Is 106 Main open on Sunday?

No, 106 Main is closed on Sundays.

Where is 106 Main located?

106 Main is located at 106 East Main Street, Durham, NC.

What is the phone number of 106 Main?

You can call 106 Main at (919) 593-0560.